When the problem becomes bigger than this I reach for my diomaceous earth (DE). Gently dusted or added to water and sprayed, this natural element often thwarts the enemy with a few applications. Tough pest problems, such as a mass invasion of stink bugs, get Neem oil treatments.
As for me. My motto is 'less is best' At the first sign of chewed leaves or spotted fruits, my first attempt is remove it by hand. Second step is basic and natural, and from there my last ditch is to send in the chickens. Organic gardeners, I recommend a bag of DE, some Bacillus Thergenus (BT), and some Neem oil. Non-organic gardeners, grab some Round up and blast it (as some of my fellow Master Gardeners love to say).
Above all, enjoy your garden. It takes work, patience, persistence and a whole lot of faith to grow those wonderful plants.